PAST: the Pathway Association Study Tool assigns your SNPs to genes and your genes to metabolic pathways. PAST transfers the attributes of your SNPs (R2, p) to the genes and identifies pathways that are significantly associated with your trait of interest.
By running PAST, either through the Shiny application or through the R console, researchers can gain a deeper understanding of the biological meaning of their GWAS results by investigating the metabolic pathways involved.
How to run PAST at MaizeGDB
MaizeGDB has three instances of PAST installed on R Shiny servers. There is a limit to running one job per server. If a link is unresponsive, please try a different server or check back later when the server becomes available. An average job takes between 30 - 90 minutes to complete.